Transcriptomic analysis of Mandarin fish brain cells infected with infectious spleen and kidney necrosis virus with an emphasis on retinoic acid-inducible gene 1-like receptors and apoptosis Q5 pathways
jueyucexu
 
Abstract:
  Infectious spleen and kidney necrosis virus (ISKNV) has caused significant economic losses in the
cultured Mandarin fish (Siniperca chuatsi) industry. The molecular mechanisms that underlie the pathogenesis of the viral infection remain poorly understood. In this study, deep RNA sequencing technique
was used to analyze the transcriptomic profiles of Mandarin fish brain cells (CPB) at progressive time
points after ISKNV infection. A total of 96,206,040 clean data from 98,235,240 sequence reads were obtained.
 
Acknowledgments:
  This work was jointly supported by Special Scientific Research Funds for Central Non-profit Institutes, Chinese Academy of Fishery Sciences (2015B05XK03) and National Natural Science Fund of China (No. 31202032).
 
References:
  [1] V.G. Chinchar, S. Essbauer, J.G. He, A. Hyatt, T. Miyazaki, V. Seligy, et al., Family
iridoviridae, in: C.M. Fauquet, M.A. Mayo, J. Maniloff, U. Desselberger, L.A. Ball (Eds.), Virus Taxonomy. Eighth Report of the International Committee Ontaxonomy of Viruses, Academic Press, San Diego, 2005, p. 145e62.
 
文章链接: 
http://www.ncbi.nlm.nih.gov/pubmed/?term=Transcriptomic+analysis